Alteration of carotid occlusion

201(5): 897-900. I g6 I .-Dogs under chloralose anesthesia show augmented reflex responses of systolic arterial pressure, mean arterial pressure, diastolic arterial pressure, and pulse rate to bilateral occlusion of the common carotid arteries over the responses of these same parameters before any a nesthesia. H yporeflexia, as indicated by these parameters, is observed when the anesthetic is chloralose and urethan, pentobarbital, or thiobarbital. Less variance in the responses as a result of alteration of the anesthetic level is observed with chloralose or pentobarbital anesthesia than with chloralose and urethan or thiobarbital anesthesia. If either chloralose or pentobarbital is to be used in studies involving the carotid sinus reflex, due consideration must be given to the 8c70 increase in response of mean ar terial pressure under chloralose anesthesia as well as the g% decrease in response of this same parameter under pentobarbital anesthesia.